PEOPLE
We are a group of people passionate about electronic technologies for medical devices, respiratory medicine and respiratory physiology. We like to challenge ourselves addressing open issues in medicine and physiology in general, but especially when concerning diagnosis and management of respiratory disorders or technologies for respiratory support, from simple CPAP devices to the most complex systems for mechanical ventilation in ICU.
STAFF
Raffaele Dellacà
Raffaele Dellaca’ has a Master degree in Information Technology Engineering from the Politecnico di Milano (1997) and a PhD degree in Biomedical Engineering (2001). Since 2011 he is Associate Professor of Biomedical Electronics at the Department of Electronics, Informatics and Biomedical engineering of the Politecnico di Milano University and has been awarded as Raine Visiting Professor at University of Western Australia, Perth, since 2016. He is responsible for the Technologies for Respiration (TechRes) Laboratory. Dr. Dellaca’ main research interests are in the area of respiratory physiology, in particular on respiratory mechanics, linear and non-linear modelling of respiratory system mechanical properties, development of new technologies for the analysis of respiration, mechanical ventilation and anaesthesia in adults and newborns. He is responsible or collaborating to several research projects sponsored by public agencies, foundations and companies. He is author of more than 100 full papers published on international peer-reviewed journals, 11 book chapters and 18 patents.
Emanuela Zannin
Dr Zannin obtained her Ph.D. and M.Sc. in Biomedical Engineering in 2010 and 2005, respectively, both from Politecnico di Milano, Italy. Her expertise is in novel technologies for monitoring lung function, diagnosing lung diseases, and personalizing respiratory support strategies, with a focus on neonatal applications. She also has a commitment toward the development of technological solutions affordable and appropriate for neonatal care in low-resource settings. Dr Zannin was a short-term visiting academic at the Murdoch Children Research Institute (Melbourne, Australia) in 2011 and at the University of Western Australia in 2018. She was awarded a Fellowship of the European Respiratory Society for a project on lung function markers of chronic lung disease of infancy that she carried out at the University Children’s Hospital (Basel, Switzerland) between 2016 and 2018. Dr Zannin main career achievement is the development of a new method for monitoring lung volume recruitment. This method has been patented in 2006, validated in preclinical models of respiratory distress syndrome (Dellacà et al. 2009 and 2011) and lung prematurity (Zannin et al. 2014), and applied in human infants during different respiratory support modes (Dellacà et al. 2013, Zannin et al. 2016). This method has been implemented into a neonatal mechanical ventilator, which is now commercially available. Between 2008 and 2016, Dr Zannin was co-founder of Restech srl, a spin-off company of Politecnico di Milano, aiming at developing and commercializing novel biomedical devices for lung function evaluation. Dr Zannin is author of 36 peer-reviewed papers and five book chapters. She serves as Review Editor in Frontiers in Network Physiology and as a regular reviewer for journals publishing pediatric and respiratory medicine articles. She is a member and elected secretary of the “Neonatal Intensive Care Unit and Pediatric Intensive Care Unit” Group of the European Respiratory Society.
Chiara Veneroni
Chiara Veneroni has a Master and a PhD degree in Biomedical Engineering from Politecnico di Milano (2009 and 2014). Since 2014 she has a Post-Doc position at the Department of Electronics, Informatics and Biomedical engineering of Politecnico di Milano University. Her interest is in respiratory physiology and respiratory supports. Her primary focus is the management of preterm infants from the resuscitation at birth till their respiratory management in intensive care units. However, she is also interested in studying the pathological changes of small airways and lung parenchyma in the adult population. She studies methods for bedside lung function assessment and respiratory system’s mathematical models to improve our understanding of patho-physiological changes in the respiratory system and optimize the treatments. She supervised more than 20 Bachelor and Master theses. She attended several international congresses. She published 18 manuscripts in peer-reviewed journals.
Davide Bizzotto
Davide Bizzotto obtained his MSc in Biomedical Engineering in October 2017 at Politecnico di Milano. Since November 2017, he joined TECHRes Lab, working on the development of new technologies and methods for the respiratory monitoring of the salt-water balance during physical exercise (Smart hydration garment – Smyt). In February 2019, he started a Ph.D. aimed to investigate the role of the upper airways and physiological breathing pattern variability during non-invasive ventilatory (NIV) support to develop new ventilation modes able to improve the effectiveness of NIV. He developed a blower-based mechanical ventilator to perform real-time Forced Oscillation Technique (FOT) analysis during invasive and non-invasive ventilation currently employed in numerous studies aimed to optimize the ventilatory strategies. He supervised various MSc and BSc thesis in the field of his Ph.D. and the development of a new device for evaluating lung function in asthmatic horses.
Stefano Robbiani
Stefano Robbiani graduated in MSc Biomedical Engineering in April 2020 at Politecnico di Milano with the thesis “Effects of a novel treatment on fetal lung pressure and breathing pattern monitored by a custom-made implantable device in an experimental model of Congenital Diaphragmatic Hernia”, in collaboration with the University of Western Australia (UWA). Since November 2020 he is PhD student at TechRes Lab working on a new device for lung diagnosis based on the combination of the electronic nose technology and Forced Oscillation Technique (FOT). He is working on a project funded by Regione Lombardia consisting in a register for COVID 19 patients, involving two universities and 6 clinical centers. During his period in the laboratory he took part in the realization of a wearable device for real time swimming monitoring, continued the work on his master thesis on Congenital Diaphragmatic Hernia (CDH) in collaboration with UWA, and collaborated with Chiesi Farmaceutici on medication delivery in upper airways.
Sofia Poletto
Sofia Poletto graduated in MSc Biomedical Engineering in April 2021 at Politecnico di Milano with the thesis “A novel closed-circuit mechanical ventilation system to assess lung mechanics during Xenon Synchrotron Radiation Imaging”, in collaboration with European Synchrotron Radiation Facility, Grenoble. Since May 2021 she is a PhD student at TechRes Lab working on the project “New technologies for safe and effective respiratory support during emergencies and in low-resource settings – SAFER”, which won the Polisocial Award 2020. The aim of her research is the development of a non-invasive mechanical ventilator which needs to be cheap, with low energy consumptions and independent from oxygen sources, in order to be disposable also in contexts where there is lack of resources, for example in African countries or in high emergency conditions, like the one encountered during Covid-19 pandemic. She is currently co-advisor of two Master thesis students.
Beatrice Bonomi
Beatrice Bonomi graduated in MSc Biomedical Engineering in October 2021 at Politecnico di Milano with the thesis “Novel approaches for bedside monitoring of upper airways patency in newborns during respiratory support”. Since November 2021 she is a PhD student at TechRes Lab.
Francesco Togninalli
Francesco Togninalli graduated in MSc Biomedical Engineering in April 2021 at Politecnico di Milano with the thesis “A sensorized swimsuit for real time data monitoring in professional swimmers”, in collaboration with Tessitura Taiana and F.I.N.P. (Federazione Italiana Nuoto Paralimpico). Since July 2021 he joined the TechRes Lab as a research assistant, working on projects in the same field of his MSc thesis. The aim of his research is to develop new wearable devices able to measure and monitor sport activity and physiological information in professional athletes, in particular integrating new technologies for non-invasive breath monitoring.
MASTER THESIS STUDENT
Lorenzo Tassello
Thesis title: Development of wearable system for vital parameters monitoring during cycling
Tommaso Pieristé
Thesis title: An algorithm for extracting ventilation trigger signal from surface EMG
Aurora Pierantozzi
Thesis title: An electronic nose for online exhaled breath analysis
Andrea Togni
Thesis title: Optimization of a novel compact oxygen concentrator for low-resource settings
Marta Dotti
Thesis title: A novel ventilatory platform for neonatal non-invasive ventilation in low-resource settings
Emanuele Ghilotti
Thesis title: A novel device for non-invasive respiratory support in emergency conditions
Elena Barzanti
Thesis title: Study of an oscillatory mechanics criterion for surfactant therapy administration in preterm newborns
Alberto Perfetti
Thesis title: Development of a new HFO ventilator
Gioia D'Andrea
Thesis title: Optimization of laparoscopy parameters
Marko Mladjenovic
Thesis title: Electronic nose applications in the Health field
PAST MEMBERS
STAFF
Valeria Ottaviani
Thesis Title: Improving respiratory support of preterm newborns by bedside characterization of lung mechanics and respiratory control
Valeria Ottaviani obtained her MSc in Biomedical Engineering in April 2017 at Politecnico di Milano. Since June 2017, she joined TECHRes Lab, working on the development of wearable device to analyse breathing pattern and saline/water balance during cycling (Smart hydration garment – Smyt). In November 2017, she started a Ph.D. aimed at improving respiratory support of preterm newborns by bedside characterization of lung mechanics and respiratory control. She developed tools that clinicians can use at the bedside to evaluate factors that may impact infants’ inadequate gas exchange, as accuracy of pressure and volume delivered, respiratory system mechanic, thoracoabdominal movements, respiratory drive and central breathing pattern generator. She supervised five MSc and one BSc thesis. Moreover, she participates at the organization and development of practical session of the “Corso per formatori in tecnologie per l’assistenza respiratoria neonatale” in collaboration with the Società Italiana di Neonatologia (SIN).
She Obtained her PhD in Bioengineering in November 2021.
Master thesis
Veronica Gimignani
Thesis Title: A novel device based on forced oscillation technique for tailoring intra-abdominal pressure during laparoscopy
Alessandro Cacciatore
Thesis Title: A sustainable deep learning approach for limbs’ detection in preterm infants depth images
Moutaz Abou El Ata
Thesis Title: Proof of concept of a novel non-invasive respiratory support device for low resource settings
Sara Baccetti
Thesis Title: Proof of concept of a novel non-invasive respiratory support device for low resource settings
Nunzio Barletta
Thesis title: Non-invasive assessment of the upper airways’ modulation during breathing
Benjamin Herbelin
Internship title: Automatic samples treatments for electronic nose analysis of biological samples
Margherita Pappolla
Thesis title: Design and development of an experimental set-up for real-time VOCs analysis of exhaled breath
Thomas Carrassi
Thesis Title: A compact and wireless lung function test device for respiratory medicine
Annalisa Torquati
Thesis Title: A novel E-nose device for diagnosing respiratory diseases
Davide Goshen
Thesis Title: Design and development of an experimental set-up for enabling lung function test by oscillometry in spontaneously breathing infants
Aurora Montanarini
Thesis title: Development of a control unit and user interface for a novel mechanical ventilator specifically designed for use in low resource settings
Giovanni Merighi
Thesis title: Proof-of-Concept of a Built-In Oxygen Concentrator for a Novel Non-Invasive Mechanical Ventilator for Low-Resource Settings
Rodolfo Massara
Thesis title: A new ventilator setting for MRI applications
Sara Rinaldi
Thesis title: Realization of upper airways anatomical models
Diana Zăvoianu
Internship title: Development of a flow-volume simulator